a case of mesothelioma – The voice of the doctors

by GIUSEPPE CINQUEPALMI

80s woman with previous breast cancer undergoing radical mastectomy and right axillary lymphadenectomy (2021) and currently on hormone therapy, recent removal of ulcerated basal cell carcinoma (January 2023), myelodysplastic syndrome, type 2 diabetes mellitus, chronic renal failure, has plaques pleural on chest x-ray as she suffers from asbestosis (spouse employed by Officine Calabresi in Bari).

Vaccinated for SARS-CoV-2
In 2022 he fell ill due to COVID-19 infection.

In November 2023, due to the appearance of worsening dyspnea, he performed a chest x-ray which revealed the presence of “Left massive pleural effusion”. Therefore he is admitted to the Thoracic Surgery Department of the Polyclinic of Bari. During hospitalization he performs TOTAL ODY CT which at the Thoracic level detects:

(On the blood count, the increase in monocytes correlates with the increase in platelets)

EPIDEMIOLOGICAL DATA (Chamber of Deputies 23 Nov 2018)

It is curious to note the presence of mesothelioma ipsilaterally within a lung parenchyma with focal areas of ground glass characteristics of COVID-19 infection, as well as the period of onset following infection. From the epidemiological data it is also clear that the patient would have a very low probability of developing mesothelioma, if not as a consequence of a deviation of the monocyte-macrophage system, implicated in both processes, towards SARS-Cov-2 infection.

 
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