Prostate cancer: how to find out with a urine test

The prostate cancer it is a disease that mainly affects men over 40. For an early diagnosis in this age group, it is advisable to undergo specific screening, also taking into account the familiarity and ethnic origin. One of the most widespread tests is that of PSA (Prostate Specific Antigen), a test that measures the levels of a specific protein in the blood. A high PSA value can be a warning sign, but it does not always indicate the presence of a tumor or a serious oncological disease. In fact, there are several factors that can alter the PSA, sometimes making the inconclusive test, for example prostatic hypertrophy, a prostate infection, recent sexual activity or even strenuous exercise can influence the test results. In fact, less than 25% of men with an elevated PSA actually have a type of prostate cancer that requires immediate treatment.

Fortunately, today it is available a new tool which can help simplify the diagnostic path: MyProstateScore2.0 (MPS2).

Prostate cancer and urine tests

MPS2 is a non-invasive urine-based genetic test, clinically proven to determine the individual risk of prostate cancer high grade, the most aggressive and worrying. By analyzing 18 specific genes, the test provides a personalized risk score that indicates the likelihood of having this type of cancer. TO PSA differencewhich simply measures a protein level that can vary for various reasons, MPS2 investigates directly on the genes linked to the most aggressive forms of prostate cancer. This makes it a tool more specific and accurate in identifying truly dangerous tumors. A negative MPS2 result is great news: it means that the probability of having an aggressive cancer is very low, almost 100%.

advantages of mPS2

The new generation tests allow us to avoid unnecessary invasive biopsies and moments of anxiety for the patient, with considerable savings for the healthcare system, among other things. The advantages are several:

Getting more technical, MPS2 has proven to be effective in identifying tumors classified as Gleason 3+4=7 or Grade Group 2 (GG2) or higher, which therefore have a greater chance of growth and diffusion. Compared to traditional diagnostic means, MPS2 is able to avoid reducing the number of necessary biopsies by up to 41%.

prostate cancer, when to worry

Prostate cancer poses a significant threat to men’s health, especially with advancing age. Although its progression is often slow, it is essential not to underestimate the risks and adopt prevention and, above all, prevention strategies early diagnosis. Advanced age, family history and genetic predisposition are in fact risk factors to take into consideration.

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Symptoms like difficulty urinating, blood in the urine And bone pain they can only manifest themselves in the advanced stages of the oncological disease, making early diagnosis crucial. Digital rectal examination, PSA and, if necessary, ultrasound and biopsy are useful tools for an accurate diagnosis. The choice of treatment, however, varies depending on the aggressiveness of the tumor and the patient’s health status, and includes options such as active surveillance, surgery, radiotherapy, hormone therapy and latest generation drug therapies.

 
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