The paracetamol, also known as acetaminophen, is one of the most common and accessible drugs for self-medication worldwide. This active ingredient is the main component of many medicines, including Tachipirina, and is widely used to mitigate cold symptoms and to treat pain, both acute and chronic. Its ease of availability and perceived safety make it a commonly used medicine even for children and pregnant women.
Safety and risks of paracetamol
Although acetaminophen is generally considered safe when used as directed, it is crucial to be informed about the dangers of its improper or excessive use. An overdose can occur accidentally, given its presence in numerous freely marketable pharmaceutical products. For example, it is common for a person to take one Tachipirina tablet and then, to treat other symptoms, take other medicines that contain the same active ingredient, increasing the risk of overdose.
Every year, the Poison Control Center at the Niguarda hospital in Milan records thousands of cases of drug overdose, with paracetamol often at the top of the list, especially in children under six.
Symptoms and consequences of paracetamol poisoning
The initial signs of acetaminophen poisoning may be mild, such as nausea, vomiting, and excessive sweating. However, in more serious situations, liver damage, liver failure and, in the most extreme cases, death can occur. It is important to note that some individuals do not experience noticeable symptoms in the first 24 hours after excessive ingestion.
The main danger of paracetamol is thehepatotoxicitywhich can occur when the drug is taken in doses higher than recommended, in the presence of liver or kidney disease, or in case of alcohol abuse.
Recommended doses of paracetamol
- Under 10kg in weight: 7.5 mg, repeatable every 4/6 hours, maximum 4 times a day. Maximum dose for 24 hours: 30 mg.
- Between 10 and 50 kg in weight: 15 mg, repeatable every 4/6 hours, maximum 4 times a day. Maximum dose for 24 hours: 60 mg.
- Over 50kg in weight: 1 g, repeatable every 4/6 hours, maximum 4 times a day. Maximum dose for 24 hours: 4 g.
A study from the University of Leeds School of Medicine highlighted that prolonged use of paracetamol can increase the risk of heart, gastrointestinal and kidney problems.
Risk factors and preventive measures
Some factors may increase the risk of acetaminophen poisoning, including taking excessive doses, prolonged use without medical supervision, combination with other drugs containing acetaminophen, and alcohol consumption.
To reduce the risk of poisoning, it is essential:
- Follow medical indications: never exceed the recommended dose and avoid prolonged use without medical supervision.
- Avoid alcohol: Alcohol consumption may increase the risk of liver damage when taken with acetaminophen.
- Monitor symptoms: Pay attention to signs such as nausea, vomiting, abdominal pain and jaundice, and consult a doctor in case of suspicious symptoms.
- Precautions for children: Keep paracetamol and other medicines out of the reach of children to prevent accidental ingestion.
Conclusion
There Tachipirina It is an effective drug for treating fever and pain, but should be used with caution. It is essential to respect the recommended doses and be aware of the potential risks. If you have any concerns or worrying symptoms, it is always best to consult a doctor or qualified healthcare professional. Safe use of medications is essential to prevent serious health consequences.
